Mr. Hossein Soltani Nejad , Department of Stem Cells Technology and Tissue Regeneration, Faculty of Interdisciplinary Science and Technologies, Tarbiat Modares University, Iran.
Mr. Hossein Soltani Nejad is a dedicated faculty member at Tarbiat Modares University ๐ซ, specializing in gene therapy and disease diagnostics using the CRISPR/Cas system ๐งฌ. His cutting-edge work involves nanocarriers for precise gene delivery ๐. With a postdoctoral background in editing hematopoietic stem cells for immunodeficiency disorders ๐ถ and a Ph.D. in nanobiotechnology focusing on cancer diagnostics ๐ฏ, he continues to contribute significantly to biomedical innovation. Mr. Soltani has collaborated with esteemed institutions, including the University of Nebraska Medical Center ๐บ๐ธ, and is passionate about translational research bridging bench to bedside ๐งโโ๏ธ๐ฌ.
Publication Profile
Education & Experienceย
-
๐ Ph.D. in Nanobiotechnology โ University of Isfahan (2018): Focused on DNA methylation-based diagnostics for colorectal cancer.
-
๐งช Postdoctoral Research โ Tehran University of Medical Sciences (2020โ2021): CRISPR editing of stem cells in immunodeficiency patients.
-
๐ Research Fellowship โ UNMC, USA (2017): CRISPR-based GFP gene insertion in human cells.
-
๐จโ๐ซ Faculty Member โ Department of Stem Cell Technology and Tissue Regeneration, Tarbiat Modares University.
Summary Suitability
Mr. Hossein Soltani Nejad is an outstanding candidate for the Best Researcher Award, due to his innovative contributions in the fields of gene therapy, disease diagnosis, and nanotechnology. His specialized expertise in utilizing the CRISPR/Cas9 system for genome editing and applying nanocarriers for gene delivery places him at the forefront of cutting-edge research in molecular medicine and biotechnology. As a faculty member at the Department of Stem Cell Technology and Tissue Regeneration at Tarbiat Modares University, Mr. Soltaninejadโs work has directly contributed to advancements in precision medicine, therapeutic strategies for genetic disorders, and the development of novel treatments for chronic diseases, including cancer, autoimmune disorders, and Parkinson’s disease.
Professional Developmentย
Mr. Soltani Nejad continually enriches his expertise through multidisciplinary collaborations and translational research projects ๐งฌ๐ง . He engages in animal and cellular modeling for diseases such as Parkinsonโs and hemophilia ๐, employs cutting-edge nanotechnology for drug delivery and diagnostics โ๏ธ, and contributes to clinical trials in regenerative medicine ๐. He collaborates with multiple medical universities across Iran and the Pasteur Institute ๐ฅ, advancing therapeutic platforms that integrate CRISPR systems, stem cells, and targeted delivery technologies ๐. His commitment to innovation and patient-centered solutions keeps him at the forefront of molecular medicine and gene therapy development ๐.
Research Focusย
Mr. Soltani Nejadโs research centers on gene therapy and regenerative medicine, with a focus on CRISPR/Cas genome editing ๐งฌ, stem cell therapy ๐ฑ, and nanotechnology-based delivery systems ๐งซ. His work addresses a broad spectrum of diseases, including hemophilia, Parkinsonโs disease, cancer, and infectious diseases like COVID-19 ๐. By integrating biomaterials such as PEG-PLGA and functionalized peptides, he explores innovative methods for precise and effective therapeutic delivery ๐. His approach bridges fundamental science with clinical application, aiming to develop targeted, less invasive treatments for genetic and degenerative conditions across medical disciplines ๐ง ๐ฆด๐ซ.
Awards & Honorsย
-
๐ Co-Author of Highly Cited Review Article โ โClinical applications of the CRISPR/Cas9 genome-editing systemโ, published in Journal of Genes & Diseases, 2024.
-
๐งฌ Lead Contributor on CRISPR and Precision Medicine Integration โ Recognized for authoring pivotal reviews on CRISPR, CAR-T, and AI in gene therapy (2023).
-
๐ Noted for Innovation in DNA Methylation Detection โ Author of novel research using gold/silver nanoclusters in fluorescence-based cancer diagnostics (2018โ2019).
-
๐ Early Career Research Excellence โ Published internationally during postdoctoral and research fellowship phases in collaboration with global institutions (UNMC, TUMS).
-
๐ International Research Collaboration in Plant Pathology โ Contributing author to a genetic study on citrus canker published with French researchers (2015).
-
๐งช Recognized Contributor in Stem Cell and Nanomedicine โ Co-authored clinical and experimental studies on stem cell sorting and nanoparticle-based drug delivery.
Publication Top Notes
-
Khoshandam, M., Soltaninejad, H., Hamidieh, A. A., & Hosseinkhani, S. (2024, July). CRISPR, CAR-T, and NK: Current applications and future perspectives. Genes & Diseases, [ISSN: 2352-3042]. https://doi.org/10.1016/j.gendis.2023.101121
-
Khoshandam, M., Soltaninejad, H., Mousazadeh, M., Hamidieh, A. A., & Hosseinkhani, S. (2024, January). Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine. Genes & Diseases, [ISSN: 2352-3042]. https://doi.org/10.1016/j.gendis.2023.02.027
-
Zare-Zardini, H., Hatamizade, N., Haddadzadegan, N., Soltaninejad, H., & Karimi-Zarchi, M. (2022). Advantages and disadvantages of using carbon nanostructures in reproductive medicine: Two sides of the same coin. JBRA Assisted Reproduction, [ISSN: 1518-0557]. https://doi.org/10.5935/1518-0557.20210070
-
Farhangfar, S., Fesahat, F., Zare-Zardini, H., Dehghan-Manshadi, M., Zare, F., Mirsmaeili, S. M., Vajihinejad, M., & Soltaninejad, H. (2022, December). In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer. Iranian Journal of Basic Medical Sciences. https://doi.org/10.22038/ijbms.2022.66065.14524
-
Parsaeian, M. R., Haji Shabani, A. M., Dadfarnia, S., Zare-Zardini, H., Soltaninejad, H., & Forouzani-Moghaddam, M. J. (2022, October). Evaluating the biological activities of functionalized magnetic iron oxide nanoparticles with different concentrations of aqueous pine leaves extract. Journal of the Indian Chemical Society, [ISSN: 0019-4522]. https://doi.org/10.1016/j.jics.2022.100707
-
Zare-Zardini, H., Soltaninejad, H., Ghorani-Azam, A., Nafisi-Moghadam, R., Haddadzadegan, N., Ansari, M., Saeed-Banadaki, S. H., Sobhan, M. R., Mozafari, S., & Zahedi, M. (2022, September). Slow release curcumin-containing soy protein nanoparticles as anticancer agents for osteosarcoma: Synthesis and characterization. Progress in Biomaterials, [ISSN: 2194-0509, 2194-0517]. https://doi.org/10.1007/s40204-022-00197-4
Conclusion
Mr. Hossein Soltani nejad exemplifies the qualities of a Best Researcher Award recipient through his unwavering commitment to impactful, translational science. His contributions bridge fundamental research and clinical innovation, addressing some of todayโs most pressing medical challenges. With a robust academic background, international collaborations, and a portfolio of multidisciplinary projects, he is a leading force in biomedical research deserving of this prestigious recognition.