Mamta Tripathi | Medicinal Chemistry | Women Researcher Award -1632

Dr. Mamta Tripathi | Medicinal Chemistry | Women Researcher Award

Pt. Ravishankar Shukla University, India

👨‍🎓Profiles

🎓 Early Academic Pursuits

Dr. Mamta Tripathi began her academic journey with a Bachelor of Science (B.Sc.) degree in Chemistry, Botany, and Biotechnology from G.D. Rungta College of Science & Technology, Bhilai, earning an impressive 70.88% in 2010. She then completed her Master of Science (M.Sc.) in Chemistry from Pt. Ravishankar Shukla University, Raipur, graduating as a gold medalist with a stellar 74.38% in 2012. Her academic excellence was further solidified when she secured the 1st position in the M.Sc. merit list, earning four gold medals in 2013. She also pursued a Bachelor of Education (B.Ed.) degree, achieving 79.88% in 2013, showcasing her dedication to both science and pedagogy.

🧑‍🔬 Professional Endeavors

Dr. Tripathi's professional journey is marked by significant milestones. She served as an INSPIRE Research Scholar from 2013 to 2018 at Pt. Ravishankar Shukla University, Raipur, where she pursued her doctoral studies alongside teaching. She later worked as a Guest Lecturer at the same university in 2019-2020. Currently, she is contributing to education as a teacher at Swami Atmanand Government English Medium School, Ahiwara, Bhilai. Additionally, she has five years of teaching experience in schools, highlighting her versatility in academic roles.

📚 Contributions and Research Focus

Dr. Tripathi’s Ph.D. thesis, titled “Studies on Hydroxamic Acid Metal Complexes as Nucleic Acid Binder and Enzymatic Inhibitors,” explores the biological properties of hydroxamic acid-metal complexes. Her research demonstrated groundbreaking findings, identifying DNA/RNA binding parameters of these complexes using UV-Visible Spectroscopy, Fluorescence Spectroscopy, and Molecular Docking techniques. She further investigated their enzymatic inhibition potential and cytotoxicity against MCF-7 breast cancer cells, with copper-hydroxamic acid complexes emerging as the most promising candidate.

🌟 Impact and Influence

Her research has significantly advanced understanding in the field of chemical biology, particularly in nucleic acid interactions and enzymatic inhibition. Dr. Tripathi’s work holds potential for future in-vivo studies and therapeutic applications, offering valuable insights into cancer treatment mechanisms.

📖 Academic Cites

Dr. Tripathi’s dedication to research is evident in her impactful publications and recognition in the scientific community. She has received prestigious accolades, including the National Young Scientist Award (2016) and the State Young Scientist Award (2017), cementing her position as an influential researcher.

💻 Technical Skills

Dr. Tripathi is proficient in a range of advanced technical techniques, including UV-Visible Spectroscopy, Fluorescence Spectroscopy, Rp-HPLC, NMR, Gel Electrophoresis, and Molecular Docking Analysis. She is adept at using computational tools like Auto Dock and Hex Software, which significantly contributed to her research findings. Her high presentation skills and computer efficiency further underscore her technical prowess.

🏫 Teaching Experience

With over five years of teaching experience, Dr. Tripathi has demonstrated her ability to guide and mentor students at various academic levels. Her roles as an INSPIRE Research Scholar and Guest Lecturer allowed her to blend research with teaching, inspiring a new generation of learners.

🌍 Legacy and Future Contributions

Dr. Tripathi’s legacy is built on her innovative research in chemical biology and dedication to education. She is committed to advancing her work on hydroxamic acid-metal complexes, with a focus on their potential in cancer treatment. Her passion for teaching ensures she will continue to inspire and mentor future scientists, leaving a lasting impact on both academia and the scientific community.

🏅 Awards and Recognitions

INSPIRE Fellow, financially supported by the Department of Science & Technology, India. National Young Scientist Award, Indian Council of Chemists. State Young Scientist Award, Chhattisgarh Young Scientist Award. Four gold medals for academic excellence in M.Sc..

📖Notable Publications

Nucleic acid binding affinity and antioxidant activity of N-m-Tolyl-4-Chlorophenoxyacetohydroxamic acid

Authors: Khilari, R., Chauhan, S., Tripathi, M., Das, D., Sarkar, A.
Journal: Scientific Reports
Year: 2024

Binding interaction of four azo linked copper (II) complexes with Human Serum Albumin (HSA): Spectroscopic and molecular docking explorations

Authors: Tripathi, M., Chauhan, S., Princess, R., Guha, S., Sarkar, A.
Journal: Results in Chemistry
Year: 2024

Engineering the future with hydrogels: advancements in energy storage devices and biomedical technologies

Authors: Sharma, A.K., Sharma, R., Pani, B., Sarkar, A., Tripathi, M.
Journal: New Journal of Chemistry
Year: 2024

In-vitro and in-silico analysis and antitumor studies of novel Cu(II) and V(V) complexes of N-p-Tolylbenzohydroxamic acid

Authors: Tripathi, M., Thakur, Y., Syed, R., Verma, B., Pande, R.
Journal: International Journal of Biological Macromolecules
Year: 2024

Nucleic acids: Components, nomenclature, types, and protection method

Authors: Tripathi, M., Sarkar, A., Mahilang, M.
Journal: Handbook of Biomolecules: Fundamentals, Properties and Applications
Year: 2023

 

Martin Gilar | Chromatography | Best Researcher Award

Dr. Martin Gilar | Chromatography | Best Researcher Award

Waters Corporation, United States

👨‍🎓Profiles

🎓 Early Academic Pursuits

Dr. Martin Gilar completed his Ph.D. in Analytical Chemistry in 1996 from the Institute of Chemical Technology in Prague. His thesis, focused on the chiral separation of dihydropyridine calcium antagonists, established his early interest in complex analytical challenges. With an MSc in Chemistry from the same institution, Dr. Gilar also gained expertise in organic technology, further refining his skills with a certificate in Pharmaceutical Analytical Methods from the Institute of Medical Postgraduate Education, Charles University.

💼 Professional Endeavors

He began his career as a Senior Staff Scientist at the Faculty Hospital of Charles University, Prague, where he led clinical studies and developed methods for drug monitoring and enantioseparation. His subsequent work at the National Institute of Health in Prague saw him pioneering capillary gas chromatography and high-performance liquid chromatography methods to phenotype cytochrome P450 markers. He joined Waters Corporation in Milford, Massachusetts, where he continues to serve as a Research Fellow. Over more than two decades at Waters, he has made transformative advancements, from LC-MS analysis of oligonucleotides to multi-dimensional separations of complex proteins and peptides. He also contributed to the commercialization of impactful products like RapiGest and HILIC SPE plates, underscoring his contributions to both academia and industry.

🔬 Contributions and Research Focus

His research is deeply rooted in separation science, particularly in liquid chromatography (LC), ultra-performance liquid chromatography (UPLC), and LC-MS methods. He has explored diverse biomolecules, from oligonucleotides to glycopeptides, establishing techniques that have refined the precision of these separations. His pioneering work includes the development of multi-dimensional protein separation techniques with MS detection and contributions to capillary electrophoresis instrumentation.

🌍 Impact and Influence

With over 80 publications in peer-reviewed journals, Dr. Gilar has made a significant impact on analytical chemistry, particularly in chromatography and oligonucleotide analysis. His methodologies are widely adopted in fields spanning pharmaceutical sciences, biotechnology, and clinical diagnostics. His expertise is further recognized by prestigious accolades such as the Jaroslav Janak Medal from the Czech Academy of Science and the Chromatographic Society Jubilee Medal, underscoring his lasting influence in chromatography.

📈 Academic Citations and Patents

His innovations are not only influential in publications but also in patents. He holds several U.S. and international patents, including patents for solid-phase extraction devices and mass-spectrometric purification methods for biopolymers. These innovations have facilitated efficient sample preparation and complex biopolymer purification, enabling more accurate and high-throughput analyses. His work continues to be highly cited in academic circles, reflecting its foundational impact on modern analytical techniques.

🛠️ Technical Skills

His technical expertise spans LC, UPLC, HPLC, and capillary electrophoresis for both qualitative and quantitative analysis. He has a deep knowledge of ion-pairing techniques, hydrophilic interaction chromatography (HILIC), and two-dimensional liquid chromatography (2D-LC). His extensive experience with mass spectrometry (MS) and advanced detection systems has also supported his development of industry-leading techniques in protein, peptide, and oligonucleotide analysis.

🧑‍🏫 Teaching Experience and Mentorship

Throughout his career, Dr. Gilar has been committed to teaching and mentoring the next generation of scientists. His early role as a Staff Scientist at Northeastern University included supervising Ph.D. students and developing analytical instrumentation. His ongoing work at Waters Corporation has also involved leading and managing research teams, fostering a collaborative environment that drives innovative research.

🌟 Legacy and Future Contributions

His contributions have established a legacy in chromatography, particularly in innovative separation techniques and practical applications in biotechnology. His continued research at Waters Corporation promises to advance analytical chemistry, driving the field toward more precise, efficient, and reliable methods. As he remains active in both research and mentorship, His influence is set to endure, shaping the analytical landscape for years to come.

📖Notable Publications